Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 31.00 | |
200 mg | In stock | $ 46.00 | |
250 mg | In stock | $ 50.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. |
In vitro | Beclomethasone dipropionate (BDP) is an anti-inflammatory corticosteroid available for the treatment of asthma and allergic rhinitis (AR). BDP is previously developed as aqueous nasal formulations for the treatment of AR. BDP is also available in dry nasal aerosol formulations as chlorofluoro carbon (CFC) metered-dose inhaler nasal sprays, but CFC-containing formulations have been withdrawn from the market and currently are not available.BDP hydrofluoroalkane (HFA) inhalation aerosol currently is available for patient use and indicated for the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older.BDP HFA nasal aerosol, an intranasal aerosol formulation, has been developed recently for the treatment of AR. |
Synonyms | Beclovent, Beclomethasone dipropionate, Beconase, Vancenase |
Molecular Weight | 521.04 |
Formula | C28H37ClO7 |
CAS No. | 5534-09-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (105.56 mM)
Ethanol: 18 mg/mL (34.55 mM)
You can also refer to dose conversion for different animals. More
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Beclometasone dipropionate 5534-09-8 Endocrinology/Hormones Glucocorticoid Receptor Beclomethasone Dipropionate iNOS 16HBE cells STAT-1 Beclovent Beclomethasone dipropionate Beclometasone Dipropionate Beconase Beclomethasone Inhibitor Beclometasone inhibit Vancenase asthma inflammation inhibitor